منابع مشابه
Mannosylated biodegradable polyethyleneimine for targeted DNA delivery to dendritic cells
BACKGROUND To establish a potential gene-delivery system with the ability to deliver plasmid DNA to dendritic cells (DCs) more efficiently and specifically, we designed and synthesized a low-molecular-weight polyethyleneimine and triethyleneglycol polymer (PEI-TEG) and a series of its mannosylated derivatives. METHODS PEI-TEG was synthesized from PEI2000 and PEI600 with TEG as the cross-linke...
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In the present study, the interactions of three different lithium species Li+, Li3+ and CH3Li with several different sites of the most stable tautomers of DNA nucleo-bases are presented. This investigation is based on the results of thermochemical properties, Quantum Theory of Atoms in Molecules (QTAIM) and Natural Bond Orbi...
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Polyethyleneimine (PEI) is known for its metal-coordinating properties and in its crosslinked form has applications in different areas ranging from drug delivery to waste water treatment and recovery of trace metals. With the aim to regulate the coordination environment of Cu(I) and Cu(II) ions in marine coatings, we have prepared a triazole cross-linking agent with 'soft' coordination that can...
متن کاملPolyethyleneimine-Coated Capillaries for the Separation of DNA by Capillary Electrophoresis
Currently, the microscopic understanding of DNA structure and function is a major problem of widespread interest. Recently, capillary electrophoresis (CE) has arisen as an effective and accessible method for the fast resolution of the microscopic constituents of complex mixtures. Molecular sieving with diluted solutions of entangled linear polymers such as polyacryamide (PAA)1−3 cellulose deriv...
متن کاملImmunostimulatory characteristics induced by linear polyethyleneimine-plasmid DNA complexes in cultured macrophages.
Intravenously injected plasmid DNA (pDNA) complexed with cationic liposome (lipoplexes) caused NF-kappaB-mediated cytokine production from macrophages, induced by CpG sequence in the pDNA. We have reported that cytokine production caused by linear polyethyleneimine (PEI)-pDNA complexes (PEI polyplexes) was much lower than that caused by lipoplexes (Kawakami, S., Ito, Y., Charoensit, P., Yamashi...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2014
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.11.1620